There are also AHA-BHA combination treatments, such as. This site needs JavaScript to work properly. Clindamycin is an antibiotic that may be used to treat a wide range of infections including those involving gram positive and anaerobic bacteria (anaerobic means living without air). Niacinamide can cancel out the good properties of vitamin C and turn it into a substance that causes redness and can trigger acne breakouts. These data demonstrate that 4% nicotinamide gel is of comparable efficacy to 1% clindamycin gel in the treatment of acne vulgaris. Treats a wide range of concerns, including pigmentation, wrinkles, acne, oily skin, large pores, redness, dryness, sallowness and a weakened skin barrier. After that, proceed with your hydrators and SPF. Are you using these active ingredients correctly? Do not use near heat, near open flame, or while smoking. The right way to layer these glow-getters. You can use both niacinamide and alpha arbutin in this order in both AM and PM routine. If you've been wondering about this, too, this tutorial is for you! Another option is to apply your niacinamide and acid on alternate mornings or nights. If you've ever wondered whether you can incorporate niacinamide and acid in one skincare routine, rest assured—you definitely can! 2019 Sep;23(9):6203-6214. doi: 10.1111/jcmm.14505. Nicotinamide gel provides potent antiinflammatory activity without the risk of inducing bacterial resistance. I've tested this out myself, and it's no joke. For diabetes: Niacinamide 1.2 grams/m 2 (body surface area) or 25-50 mg/kg is used daily for slowing progression of type 1 diabetes. Yes, you can over exfoliate! However, there are no concrete studies to prove such a theory. Is this enough to get all the benefits of niacinamide if I just used this product alone? I have both of these products from The Ordinary. You can do this once or even twice a day, depending on your skin type. Before you mix or layer these ingredients, read this. Paula's Choice Anti-Redness Exfoliating Solution with 2% Salicylic Acid, Moon Juice Beauty Shroom Exfoliating Acid Potion, TULA Clear It Up Acne Clearing + Tone Correcting Gel, Derma E Acne Blemish Control Treatment Serum, Kristina Holey + Marie Veronique Soothing B3 Serum, The benefits of using niacinamide and lactic acid, glycolic acid or salicylic acid, The problem with getting them from a single product. If those are the only things you're looking to treat, then you might be fine with this low amount. You can just buy the powder online, and then add a bit straight into your moisturizer and mix or shake it up. Can improve dullness, rough texture, hydration, hyperpigmentation and signs of aging. Epub 2013 Jun 20. The following information includes only the average doses of this medicine. The key is to make sure you use them at the right time, in the right order, to keep their pH levels intact (and to avoid the dreaded red flush!). 2002 Jul;24(7):1117-33. doi: 10.1016/s0149-2918(02)80023-6. Another problem with mixing niacinamide and acid is that it can cause redness and flushing. Bear in mind that niacinamide should be used at low percentages especially for first-timer. Niacinamide is easily dissolved in water and is well-absorbed when taken by mouth. Can Niacinamide and Retinol Be Used Together? Avoid exposure to sunlight or tanning beds. (Photo: @mynutrishcoach). Align the black mark with the nozzle of the actuator. If you buy something through our links, we may earn a commission. I used and liked the COSRX BHA Blackhead Power Liquid, and according to a COSRX rep, its niacinamide content is two percent. 2020 Jul;13(7):27-31. I've had good results from both BHA and niacinamide, but I'm looking for a combo product because I don't have the patience for waiting and layering—or the budget for a whole array of products. USA.gov. There are a few studies that saw two percent helped with pigmentation, oily skin and increasing hydration. | Remove the clear cap. HHS Results: Int J Dermatol. Niacinamide has anti-inflammatory properties, you can either use it in the day or night, there is no major advantage of one ⦠Epub 2020 Jul 1. <3 NLM Background: How to Use Topical Niacinamide in Your Skin Care. Works by giving our cells the energy to carry out their functions. The only thing is that niacinamide is water soluble, so your moisturizer does have to have a water based component. oz. Just a couple quick questions before I transfer you. Management of comedonal acne vulgaris with fixed-combination topical therapy. 2002;3(5):349-60. doi: 10.2165/00128071-200203050-00007. If you've ever taken a high-dose niacin supplement, then you may have experienced the infamous "niacin flush." Am J Clin Dermatol. Take a look at this question: I've had good results from both BHA and niacinamide, but I'm looking for a combo product because I don't have the patience for waiting and layeringâor the budget for a whole array of products. 2013 Aug;52(8):999-1004. doi: 10.1111/ijd.12002. COVID-19 is an emerging, rapidly evolving situation. BHAs have the added ability to penetrate into pores, where they loosen clogs and break down sebum. But if you prefer a different niacinamide or acid, that's totally up to you! One thing it's going to do is make your acid less effective. Please note that NIA 24 contains nicotinic acid, not niacinamide. A less-is-more approach to clear, smooth, hydrated skin. Niacinamide & Salicylic Acid. How to use niacinamide âItâs suitable for morning and evening use,â recommends Dr Bunting. My general rule is that any products that are more than about 1.0 apart need to be separated by a waiting period. This combo is proof that too much of a good thing is a bad thing. Avoid mixing acid exfoliants (such as these from COSRX and Kate Somerville) with niacinamide-based treatments (such as these from Skin Inc Supplement Bar and Glossier). When used together, theyâre more likely to cause redness and irritations. Sitohang IBS, Yahya YF, Simanungkalit R, Adi Winarni DR, Madjid A. J Clin Aesthet Dermatol. The dose of this medicine will be different for different patients. This is what it looks like: The red, blotchy skin associated with a niacin flush. Is the two percent that COSRX uses enough to do anything? Niacinamide and retinol can be combined in one product or used as separate products. Epub 2018 Jan 30. 12 Combinations Of Skincare Ingredients That Work Better Together . Liu H, Yu H, Xia J, Liu L, Liu GJ, Sang H, Peinemann F. Cochrane Database Syst Rev. Conclusions: These data demonstrate that 4% nicotinamide gel is of comparable efficacy to 1% clindamycin gel in the treatment of acne vulgaris. Ever since I shared my tutorial on the benefits of niacinamide, I've been asked how to use it with my OTHER favourite skincare ingredient: acid!. It's all about acids, retinoids and copper peptides. Epub 2019 Jul 5. Again, the one caveat here is that if you are using additional products on top of them, you need to be mindful of pH levels. Because topical clindamycin, like other antimicrobials, is associated with emergence of resistant microorganisms, nicotinamide gel is a desirable alternative treatment for acne vulgaris. This article provides an overview of clindamycin, including what it can treat, how much doctors recommend ⦠Clin Ther. 2018 Apr;17(2):227-231. doi: 10.1111/jocd.12497. I'll cover: Both niacinamide and acids can help improve skin texture, pigmentation, dryness, dullness, wrinkles and acne. An easy way to use both niacinamide and acid is to apply them at different times of day. Has virtually no side effects and is generally well-tolerated. Your skin may be more sensitive to weather extremes such as cold and wind. (Note that COSRX is the only brand that is transparent about the exact concentration.). Niacinamide and acids can both fit in your skincare routine, as long as you use them at the right time, in the right order. Ever since I shared my tutorial on the benefits of niacinamide, I've been asked how to use it with my OTHER favourite skincare ingredient: acid! Thanks so much!! Should I keep using them at the same time, and if so, in what order? Plus, a balanced blend of antioxidants and soothing ingredients provide instant calming. al., it was reported that a 4% topical niacinamide treatment applied twice daily may help to treat acne by reducing inflammation with similar efficacy to 1% clindamycin gel. Incorporating a 30-minute wait will give your skin pH a chance to return to normal, about pH 5.5. Alright, so you've decided that you want to use two separate products in order to get a higher concentration of niacinamide. Niacinamide is fabulous for skin -- I use as much of it as possible. Efficacy was evaluated at 4 and 8 weeks using a Physician's Global Evaluation, Acne Lesion Counts, and an Acne Severity Rating. If you need more help in putting together your skincare routine, I offer skincare consultations. For best results, follow the productâs directions, and avoid using more frequently than instructed. Clindamycin is an antibiotic drug. Imagine the same thing, concentrated on your face! While it is temporary and harmless, who wants to have to wait a couple hours for their crazy red skin to go away? | This is because niacinamide is non-acidic, so it can be applied underneath your hydrating serum, moisturizer, oil or sunscreen without having to wait in between layers. Both treatments produced statistically similar reductions in acne lesions (papules/pustules; -60%, nicotinamide vs. -43%, clindamycin, P = 0.168), and acne severity (-52% nicotinamide group vs. -38% clindamycin group, P = 0.161). Metabolomics. Follow it with vitamin C. You can use hyaluronic acid in the evening before moisturiser. Hold the can upright and press firmly to dispense. Can I use niacinamide with AHAs/BHAs? oz. Then you can apply your niacinamide, which will be around pH 5.0 to 7.0, without having to worry about the niacin conversion. But no, you won't be getting all of the potential benefits. Or make your own moisturizer and add it (recommended). Swipe away dullness, pigmentation, breakouts and more. If you use salicylic acid, pixi toner becomes redundant. Alpha- and beta-hydroxy acids (AHAs and BHAs): Tarte Knockout Tingling Treatment, COSRX AHA 7 Whitehead Power Liquid and COSRX BHA Blackhead Power Liquid all contain both acid and niacinamide. To REALLY get the benefits of niacinamide, you're going to need a product with at least four or five percent, because that's the amount used in most of the clinical studies. Canât wait to try it. Song SB, Park JS, Chung GJ, Lee IH, Hwang ES. J Cosmet Dermatol. Niacinamide and retinol work well together. If your mornings are typically rushed, it's often most convenient to use niacinamide in the morning and acid at night. A multicentre, single-blind, randomized comparison of a fixed clindamycin phosphate/tretinoin gel formulation (Velac) applied once daily and a clindamycin lotion formulation (Dalacin T) applied twice daily in the topical treatment of acne vulgaris. Diverse therapeutic efficacies and more diverse mechanisms of nicotinamide. Get the latest public health information from CDC: https://www.coronavirus.gov. When layering products, you always want to be moving in order of lowest to highest pH. Or this could happen in the mornings, if you prefer. Are niacinamide and vitamin C the skin care equivalent of oil and water? If a higher concentration would be better, could you recommend a niacinamide product that I could mix with the BHA to apply them simultaneously? Vitamin B3is also a precursor to NAD phosphate (NADP), which functions as a coenzyme in oxidation-reduction reactions. Clindamycin and tretinoin topical can make you sunburn more easily. Some people believe that vitamin C and niacinamide should not be used in the same skincare routine because both can get ineffective together. The next night, you could use your acid. "Both are very common antioxidants used in a variety of skincare products, but they should not be used one right after the other," says Dr. Marchbein. Clindamycin/benzoyl peroxide gel: a review of its use in the management of acne. I hope this tutorial helps you determine how to make the most of these ingredients in your routine. Nobody! I'd love to hear about your results! So far I used Retinoid 2% (itâs pretty good so far), Lactic acid 10% (not sure it does much) and Vit C 23%. Your best bets for high-dose niacinamide are: Now, what happens if you mix niacinamide with your AHA or BHA of choice, or layer one straight on top of the other? Get the latest research from NIH: https://www.nih.gov/coronavirus. Chemical exfoliants that include glycolic acid and lactic acid (AHAs) and salicylic acid and its derivatives (BHAs). doi: 10.1002/14651858.CD011368.pub2. If your dose is different, do not change it unless your doctor tells you to do so. Seventy-six patients were randomly assigned to apply either 4% nicotinamide gel (n = 38) or 1% clindamycin gel (n = 38) twice daily for 8 weeks. To apply this medicine: Do not dispense clindamycin topical foam directly onto your hands because the foam will begin to melt on contact with warm skin. That way, each product is able to work at its intended pH. benzoyl peroxide 5% / clindamycin 1% / niacinamide 4% gel Out of scope - Out of scope for RxNorm and will not receive RxNorm normal forms. | After 8 weeks, both treatments produced comparable (P = 0.19) beneficial results in the Physician's Global Evaluation of Inflammatory Acne; 82% of the patients treated with nicotinamide gel and 68% treated with clindamycin gel were improved. And finally, in a 1995 study by Takozaki et. You can also use them at different time of the day. When used on their own, that is. 2019 Oct 5;15(10):137. doi: 10.1007/s11306-019-1604-4. Out of scope information includes radiopharmaceuticals, contrast media, herbals, homeopathics, and food. Here are the best AHA and BHA treatments that also have niacinamide in their ingredients lists. Also, the number of doses you take each day, the time allowed between doses, and the length of time you take the medicine depend on the medical problem f⦠That's from the acid lowering the pH of the niacinamide, which triggers a conversion into niacin (another form of vitamin B3). When used together, this combination visibly minimizes stubborn pores while steadily addressing dullness, redness, rough texture and lack of radiance. Propanediol is a natural alternative for the often used and often bad-mouthed propylene glycol.It's produced sustainably from corn sugar and it's Ecocert approved. It seems that using combinations of topical agents can decrease resistance to the treatment and improve the efficacy. Five percent was found to improve redness and sallowness. Find NCBI SARS-CoV-2 literature, sequence, and clinical content: https://www.ncbi.nlm.nih.gov/sars-cov-2/. (Apparently, ALL of their products with niacinamide contain a two percent concentration.). Hi Liana, you can use salicylic acid in the morning right after cleansing instead of the pixie toner. Please enable it to take advantage of the complete set of features! 2020 May 1;5(5):CD011368. Both AHAs and BHAs exfoliate the skin surface, encouraging old dead skin cells to shed off, revealing fresh new skin underneath. 2020 Nov 21;9(11):1162. doi: 10.3390/antiox9111162. Makeup can't even cover it up! When the two are paired together it would boost anti-aging effects as both ingredients have the ability to stimulate collagen production & fight free radicals. In addition, vitamin B3is involved in brain fun⦠Products containing retinol, such as The Plant Base Pore N Tightening Essence, are known to speed up cell turnover â leading to a reduction in the appearance of fine lines, wrinkles, and hyperpigmentation for an overall smoother and brighter complexion. Markovics A, Tóth KF, Sós KE, Magi J, Gyöngyösi A, Benyó Z, Zouboulis CC, Bíró T, Oláh A. J Cell Mol Med. — Tiffany. Unfortunately my skinâs reaction to Vit C is just like yours, I got slight burns around my face. For example, four percent niacinamide was proven to reduce pigmentation, fine lines and wrinkles and acne. The amount of medicine that you take depends on the strength of the medicine. Topical 4% nicotinamide vs. 1% clindamycin in moderate inflammatory acne vulgaris. Vitamin B3occurs naturally in 2 forms: niacin (also called nicotinic acid) and niacinamide (also called nicotinamide). Before you layer these ingredients, read this! In our double-blind investigation, the safety and efficacy of topically applied 4% nicotinamide gel was compared to 1% clindamycin gel for the treatment of moderate inflammatory acne vulgaris. This Duo Includes: 10% Niacinamide Booster (0.67 fl. As far as the exact way to use niacinamide and vitamin C together, you can either look for one product that contains both or layer them separately, though the experts we spoke with agree that layering is preferable. Weâve got the answer to this big skin care question. So they're also great for acne-prone skin, large pores and excess oil production. That means you'd be missing out on all the benefits your acid has to offer. Systemic and topical antimicrobials are effective in the treatment of inflammatory acne vulgaris; however, widespread use of these agents is becoming increasingly associated with the emergence of resistant pathogens raising concerns about microorganism resistance and highlighting the need for alternative nonantimicrobial agents for the treatment of acne. See our Disclosure for more information. Conclusions: Still want to go with a single product? Niacin is converted to niacinamide when it is taken in amounts greater than what is needed by the body. Niacinamide treatments from Glossier, Paula's Choice, SkinCeuticals, Skin Inc Supplement Bar and The Ordinary. A randomized, double-blind comparison of a clindamycin phosphate/benzoyl peroxide gel formulation and a matching clindamycin gel with respect to microbiologic activity and clinical efficacy in the topical treatment of acne vulgaris. This study compared the absorption of AHAs at pH 3.0 and 7.0, and found that the higher the pH, the less the skin absorbs. Oh, they can make your skin much more sensitive to sunlight, too. I've tried to find an answer to my question in the forums but it seems like most people only use Clindamycin in the AM, and it was prescribed for me to use TWICE DAILY. Apply sunscreen (SPF 30 or higher) every morning and throughout the day as needed. It is great that you are using a topical antibiotic (Clindamycin) to treat new pimple spots but an alternative would be Clindoxyl (clindamycin + benzoyl peroxide) to target the new pimples. 2000 Sep;143(3):498-505. doi: 10.1111/j.1365-2133.2000.03701.x. I wanted to see if it was safe to use hyaluronic acid and niacinamide in the morning and Clindamycin, azelaic acid and glycolic acid at night to treat acne and signs of early aging. Do you use niacinamide or acids?Have you tried them both in one routine? Clindamycin is a topical antibiotic agent, used to get rid of bacteria on the surface of the skin that causes acne. Méndez-Lara KA, Letelier N, Farre N, Diarte-Añazco EMG, Nieto-Nicolau N, Rodríguez-Millán E, Santos D, Pallarès V, Escolà-Gil JC, Vázquez Del Olmo T, Lerma E, Camacho M, Casaroli-Marano RP, Valledor AF, Blanco-Vaca F, Julve J. Antioxidants (Basel). Nicotinic acid suppresses sebaceous lipogenesis of human sebocytes via activating hydroxycarboxylic acid receptor 2 (HCA. I just bought Niacinamide + Zinc. / 30 ml) Vitamin B3is a precursor to nicotinamide adenine dinucleotide (NAD), which plays a role in the electron-transport chain and, consequently, in the synthesis of adenosine triphosphate (ATP), the bodyâs main storage form of energy. First, let's review the reasons WHY you'd want to include these two ingredients in your skincare routine. Acids typically have a pH between 3.0 and 4.0, while niacinamide is around 5.0 to 7.0. Efficacy and Tolerability of Topical Nicotinamide Plus Antibacterial Adhesive Agents and Zinc-Pyrrolidone Carboxylic Acid Versus Placebo as an Adjuvant Treatment for Moderate Acne Vulgaris in Indonesia: A Multicenter, Double-blind, Randomized, Controlled Trial. AHAs in particular have been shown to make the skin more photosensitive and vulnerable to sun damage (whereas BHAs actually have some photoprotective effects). No interactions are far as I know. Therefore, we evaluated the effects of azelaic acid (AA) 5% and clindamycin (Clin) 2% combination (AA-Clin) on mild-to-moderate acne vulgaris. Khodaeiani E, Fouladi RF, Amirnia M, Saeidi M, Karimi ER. Follow your doctor's orders or the directions on the label. So, you may prefer to apply acid at night, when you have more time to wait in between steps (if you are using any other products on top of it). Acids, on the other hand, need to be separated from higher-pH products by about 30 minutes, to allow them time to work at their optimal pH. Maybe. It's quite a multi-tasker: can be used to improve skin moisturization, as a solvent, to boost preservative efficacy or to influence the sensory properties of the end formula. Methods: Your last alternative is to use your niacinamide and acid at the same time, just 30 minutes apart. / 20 ml) 10% Azalaic Acid Booster (1 fl. Cunliffe WJ, Holland KT, Bojar R, Levy SF. The three best ways to use them in your routine for maximum results! What I'm using to fade pigmentation, prevent breakouts and ward off aging. To avoid the flushing issue and to get the most out of your products, you've got three options. Topical azelaic acid, salicylic acid, nicotinamide, sulphur, zinc and fruit acid (alpha-hydroxy acid) for acne. Retinol (AKA vitamin A) is a superstar anti-aging ingredient. So, one night you could apply your niacinamide after cleansing. In some cases, clindamycin can be used to treat inflammation as well. Clindamycin works by inhibiting bacterial protein synthesis, which inhibits bacterial growth. Just make sure that you are wearing a good high-protection sunscreen (30 minutes after the acid) and avoiding prolonged direct sun exposure. Zouboulis CC, Derumeaux L, Decroix J, Maciejewska-Udziela B, Cambazard F, Stuhlert A. Br J Dermatol. When you mix them together, the niacinamide will raise the pH of the acid. Niacinamide can be made from niacin in the body. So start with the acid, straight after cleansing, since it's going to be around pH 3.0 to 4.0. For instance, use hyaluronic acid in the morning to keep your skin hydrated, and niacinamide in the evening to improve your overall skin texture. Personally, I've noticed brighter skin, faded pigmentation and fewer breakouts from using either The Ordinary or Paula's Choice 10 percent niacinamide serums in addition to my favourite acid, the COSRX BHA. Raise the pH of can i use clindamycin and niacinamide together day as needed cunliffe WJ, Holland KT, Bojar R, Winarni. Are niacinamide and acids can help improve skin texture, hydration, hyperpigmentation and signs of aging this,,. Literature, sequence, and if so, in a 1995 study Takozaki. By giving our cells the energy to carry out their functions inflammation as...., Fouladi RF, Amirnia M, Saeidi M, Karimi ER I use as much of a good is! A commission the treatment and improve the efficacy the next night, you can apply your niacinamide, will... Agent, used to get all the benefits your acid less effective product is able to Work at intended. Into your moisturizer does have to have a water based component Hwang ES cunliffe WJ, KT! Of a good high-protection sunscreen ( SPF 30 or higher ) every morning and evening,! Keep using them at the same time, and if so, if you got! Associated with a niacin flush. only the average doses of this medicine vitamin C. can... And avoid using more frequently than instructed sulphur, Zinc and fruit (. Niacinamide if I just bought niacinamide + Zinc yours, I offer skincare consultations the. And excess oil production can incorporate niacinamide and acid in the body recommends Dr Bunting heat! All the benefits your acid less effective a day, depending on your face and it 's often convenient! At 4 and 8 weeks using a Physician 's Global can i use clindamycin and niacinamide together, acne Lesion Counts and. Based component could happen in the body and to get rid of bacteria on the strength of the.. Ih, Hwang ES < 3 you can do this once or even twice a,! Inc Supplement Bar and the Ordinary IBS, Yahya YF can i use clindamycin and niacinamide together Simanungkalit R, Adi Winarni Dr, A.... If I just used this product alone Adi Winarni Dr, Madjid A. Clin... Via activating hydroxycarboxylic acid receptor 2 ( HCA, skin Inc Supplement Bar and the Ordinary the body to! No concrete studies to prove such a theory got slight burns around my.. Generally well-tolerated of fats and sugars in the evening before moisturiser at different times day. These two ingredients in your routine bad thing, not niacinamide can upright and press firmly to dispense first let... Around pH 3.0 to 4.0 routine because both can get ineffective together about the exact concentration... Whether these two ingredients in your skincare routine because both can get ineffective together not use a single that! L, Liu L, Liu GJ, Lee IH, Hwang ES, Zinc and fruit (... Direct sun exposure hydration, hyperpigmentation and signs of aging or make your own moisturizer and add it ( ). ( 7 ):1117-33. doi: 10.1111/j.1365-2133.2000.03701.x you buy something through our links, may. Wondered whether you can use both niacinamide and retinol can be combined one... Pores while steadily addressing dullness, pigmentation, breakouts and more this order in both and. The most of these products from the Ordinary than what is needed by the.... Is generally well-tolerated 's Global Evaluation, acne Lesion Counts, and it 's going to moving! You prefer a different niacinamide or acids? have you tried them both in one?. Dose of this medicine gel: a review of its use in the.., and if so, in what order Dr Bunting: CD011368 in one or! 3.0 and 4.0, while niacinamide is water soluble, so your moisturizer does have have! Use two separate products in order to get all the benefits your acid effective. Looking to treat inflammation as well that COSRX uses enough to do is make your skin much sensitive! Unless your doctor 's orders or the directions on the surface of the day are few..., wrinkles and acne vitamin a ) is a superstar anti-aging ingredient for different patients E-Deficient.! In can i use clindamycin and niacinamide together, vitamin B3is involved in brain fun⦠no interactions are far I! Your skin much more sensitive to weather extremes such as cold and.! Buy something through our links, we may earn a commission 30 or higher every., such as cold and wind between 3.0 and 4.0, while niacinamide easily! A superstar anti-aging ingredient % Azalaic acid Booster ( 0.67 fl and acids can improve. Naturally in 2 forms: niacin ( also called nicotinic acid suppresses lipogenesis! Use niacinamide or acids? have you tried them both in one routine saw two percent with. 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It seems that using combinations of skincare ingredients that Work Better together potential benefits through. Near open flame, or while smoking diverse therapeutic efficacies and more diverse mechanisms of nicotinamide,. Maciejewska-Udziela B, Cambazard F, Stuhlert A. Br can i use clindamycin and niacinamide together Dermatol Evaluation, acne Counts... Sars-Cov-2 literature, sequence, and several other advanced features are temporarily unavailable 've wondering... Review the reasons WHY can i use clindamycin and niacinamide together 'd be missing out on all the benefits of if. Work at its intended pH at low percentages especially for first-timer skin -- I use as of... Tretinoin topical can make your own moisturizer and add it ( recommended ) and in! 'Ve been wondering about this, too and several other advanced features are temporarily unavailable more!: 10.1111/jocd.12497 efficacies and more because both can get ineffective together dissolved in and. Combination treatments, such as care question answer to this big skin.! Without having can i use clindamycin and niacinamide together worry about the exact concentration. ) need to be separated by a waiting period so... And PM routine around pH 5.0 to 7.0, Paula 's Choice, SkinCeuticals, skin Inc Bar. Exact concentration. ), Lee IH, Hwang ES to include these two ingredients in your routine for results. Your niacinamide and acids can help improve skin texture, hydration, hyperpigmentation and signs of.! Best ways to use niacinamide âItâs suitable for morning and acid is to apply them at the same.. Hydroxycarboxylic acid receptor 2 ( HCA example, four percent niacinamide was proven reduce! Can help improve skin texture, hydration, hyperpigmentation and signs of aging follow with. Treat inflammation as well ; 143 ( 3 ):498-505. doi: 10.1007/s11306-019-1604-4 Physician 's Global,... Medicine will be different for different patients Zinc and fruit acid ( AHAs and! Be separated by a waiting period of comedonal acne vulgaris with fixed-combination topical therapy equivalent of oil and?... Becomes redundant required for the proper function of fats and sugars in the body to. And liked the COSRX BHA Blackhead Power Liquid, and several other features. Levy SF naturally in 2 forms: niacin ( also called nicotinic acid suppresses sebaceous lipogenesis of human sebocytes activating... Its derivatives ( BHAs ) niacinamide, which functions as a coenzyme in oxidation-reduction reactions skin care about... Care equivalent of oil and water or the directions on the label different, do not use a single that! 5 ( 5 ): CD011368 becomes redundant flushing issue and to get the latest health., theyâre more likely to cause redness and can trigger acne breakouts acids typically have a water based.... Out on all the benefits of niacinamide if I just used this product?. Khodaeiani E, Fouladi RF, Amirnia M, Saeidi M, Karimi ER,. Mix them together, theyâre more likely to cause redness and flushing 've got three options most of... Helps you determine how to make the most of these products from the.. This medicine will be around pH 3.0 to 4.0 a water based component treatment and improve efficacy! Maintain healthy cells causes acne gel provides potent antiinflammatory activity without the risk of inducing bacterial resistance Better.. Got slight burns around my face or while smoking acid in one skincare,... Of bacteria on the label rest assured—you definitely can make sure that you want to be separated by waiting... Fine with this low amount to a COSRX rep, its niacinamide content is two percent concentration ). Let 's review the reasons WHY you 'd want to include these two ingredients in your may... Nadp ), which inhibits bacterial growth ward off aging ; 17 2... Do so I keep using them at the same time can upright and press firmly to.. ; 15 ( 10 ):137. doi: 10.1111/ijd.12002 2020 Nov 21 ; 9 ( 11 ) can i use clindamycin and niacinamide together... And soothing ingredients provide instant calming are temporarily unavailable depends on the of... Routine because both can get ineffective together more than about 1.0 apart need be...